Clinical and hormonal effects of ethinylestradiol combined with gestodene and desogestrel in young women with acne vulgaris

D Mango, S Ricci, P Manna, GAD Miggiano, GB Serra - Contraception, 1996 - Elsevier
The effect of gestodene 75 μg (GTD) versus desogestrel 150 μg (DSG) combined with 30 μg
of ethinylestradiol (EE) on acne lesions and plasma androstenedione (A), total testosterone
(T), sex hormone binding globulin (SHBG) and “free androgen index”(FAI) was evaluated in
an open study on 19 patients aged 18–35 years affected with postpubertal or persistent non-
severe acne vulgaris. The patients were randomly allocated into two groups receiving EE-
GTD (n= 8) and EE-DSG (n= 11), 21 tablets per cycle for 9 consecutive cycles. Clinical and …
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